Reduced CSF Water Influx in Alzheimer's Disease Supporting the β-Amyloid Clearance Hypothesis.

To investigate whether water influx into cerebrospinal fluid (CSF) space is reduced in Alzheimer's patients as previously shown in the transgenic mouse model for Alzheimer's disease.Ten normal young volunteers (young control, 21-30 years old), ten normal senior volunteers (senior control,...

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Bibliographic Details
Main Authors: Yuji Suzuki, Yukihiro Nakamura, Kenichi Yamada, Hironaka Igarashi, Kensaku Kasuga, Yuichi Yokoyama, Takeshi Ikeuchi, Masatoyo Nishizawa, Ingrid L Kwee, Tsutomu Nakada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422624?pdf=render