COE loss-of-function analysis reveals a genetic program underlying maintenance and regeneration of the nervous system in planarians.

Members of the COE family of transcription factors are required for central nervous system (CNS) development. However, the function of COE in the post-embryonic CNS remains largely unknown. An excellent model for investigating gene function in the adult CNS is the freshwater planarian. This animal i...

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Bibliographic Details
Main Authors: Martis W Cowles, Kerilyn C Omuro, Brianna N Stanley, Carlo G Quintanilla, Ricardo M Zayas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4214590?pdf=render