A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition

Abstract Background Transposable elements are ubiquitous and play a fundamental role in shaping genomes during evolution. Since excessive transposition can be mutagenic, mechanisms exist in the cells to keep these mobile elements under control. Although many cellular factors regulating the mobility...

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Bibliographic Details
Main Authors: Anastasia Barkova, Indranil Adhya, Christine Conesa, Amna Asif-Laidin, Amandine Bonnet, Elise Rabut, Carine Chagneau, Pascale Lesage, Joël Acker
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Mobile DNA
Subjects:
Ty1
Integrase
Proteomic
CK2 protein kinase
Phosphorylation
Retrotransposition
Online Access:https://doi.org/10.1186/s13100-022-00284-0

Internet

https://doi.org/10.1186/s13100-022-00284-0

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