Effect of SMAC Gene on Sensitivity of Lung Adenocarcinoma Cells to Paclitaxel and Cell Viability Based on caspase-3/Bcl-2/Bax Signaling Pathway

Effect of SMAC Gene on Sensitivity of Lung Adenocarcinoma Cells to Paclitaxel and Cell Viability Based on caspase-3/Bcl-2/Bax Signaling Pathway

Objective To investigate the effect of the SMAC gene on paclitaxel sensitivity and cellular activity in lung adenocarcinoma cells based on the caspase-3/Bcl-2/Bax signaling pathway. Methods A paclitaxel-resistant cell line A549/Taxol was established for lung adenocarcinoma, and the cells were divide...

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Bibliographic Details
Main Authors: CHEN Kang, CHEN Ying, NIU Zongxin, KANG Li, ZULIPEYA·Aibaidula
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2023-04-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
caspase-3/bcl-2/bax signaling pathway
smac gene
lung adenocarcinoma cells
paclitaxel resistance sensitivity
proliferation
invasion
apoptosis
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1114

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http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1114

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