A Novel Dialkylamino GFP Chromophore as an Environment-Polarity Sensor Reveals the Role of Twisted Intramolecular Charge Transfer

We discovered a novel fluorophore by incorporating a dimethylamino group (–NMe<sub>2</sub>) into the conformationally locked green fluorescent protein (GFP) scaffold. It exhibited a marked solvent-polarity-dependent fluorogenic behavior and can potentially find broad applications as an e...

Full description

Bibliographic Details
Main Authors: Cheng Chen, Sean A. Boulanger, Anatolii I. Sokolov, Mikhail S. Baranov, Chong Fang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/9/8/234