A Novel Dialkylamino GFP Chromophore as an Environment-Polarity Sensor Reveals the Role of Twisted Intramolecular Charge Transfer

A Novel Dialkylamino GFP Chromophore as an Environment-Polarity Sensor Reveals the Role of Twisted Intramolecular Charge Transfer

We discovered a novel fluorophore by incorporating a dimethylamino group (–NMe<sub>2</sub>) into the conformationally locked green fluorescent protein (GFP) scaffold. It exhibited a marked solvent-polarity-dependent fluorogenic behavior and can potentially find broad applications as an e...

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Bibliographic Details
Main Authors:	Cheng Chen, Sean A. Boulanger, Anatolii I. Sokolov, Mikhail S. Baranov, Chong Fang
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Chemosensors
Subjects:	polarity sensor green fluorescent protein chromophore fluorogenicity twisted intramolecular charge transfer ultrafast spectroscopy multivariable analysis
Online Access:	https://www.mdpi.com/2227-9040/9/8/234

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