Molecular signature of high yield (growth) influenza a virus reassortants prepared as candidate vaccine seeds.

Molecular signature of high yield (growth) influenza a virus reassortants prepared as candidate vaccine seeds.

<h4>Background</h4>Human influenza virus isolates generally grow poorly in embryonated chicken eggs. Hence, gene reassortment of influenza A wild type (wt) viruses is performed with a highly egg adapted donor virus, A/Puerto Rico/8/1934 (PR8), to provide the high yield reassortant (HYR)...

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Bibliographic Details
Main Authors: Manojkumar Ramanunninair, Jianhua Le, Shiroh Onodera, Andrew A Fulvini, Barbara A Pokorny, Jeanmarie Silverman, Rene Devis, Jennifer M Arroyo, Yu He, Alex Boyne, Jayati Bera, Rebecca Halpin, Erin Hine, David J Spiro, Doris Bucher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776579/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776579/pdf/?tool=EBI

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