An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis

Abstract The efficacy of ponesimod and teriflunomide for the treatment of relapsing multiple sclerosis (MS) was compared in a randomized phase III trial. This study explores the exposure‐response (E‐R) relationships of efficacy end points (annualized relapse rate [ARR] and combined unique active les...

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Bibliographic Details
Main Authors: Belén Valenzuela, Per Olsson Gisleskog, Italo Poggesi, Tatiana Sidorenko, Michel Burcklen, Hilke Kracker, Juan Jose Pérez‐Ruixo
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12778