Implications of targeted next-generation sequencing for bladder cancer: report of four cases

Implications of targeted next-generation sequencing for bladder cancer: report of four cases

Abstract Background Bladder cancer is considered heterogeneous diseases with two major subgroups: non-muscle- invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MIBC). It is a major healthcare problem, and it is one of the leading causes of mortality worldwide. Genetic mutations are...

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Bibliographic Details
Main Authors: Mohamed K. Khalifa, Noha M. Bakr, Amal Ramadan, Khaled M. Abd Elwahab, Esam Desoky, Amira M. Nageeb, Menha Swellam
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Bladder cancer
Somatic mutation
Germline mutation
BRCA genes
Next-generation sequencing
Case report
Online Access:https://doi.org/10.1186/s43141-021-00182-7

Internet

https://doi.org/10.1186/s43141-021-00182-7

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