Identification of the porcine IG-DMR and abnormal imprinting of DLK1-DIO3 in cloned pigs

Identification of the porcine IG-DMR and abnormal imprinting of DLK1-DIO3 in cloned pigs

Correct reprogramming of the DLK1-DIO3 imprinted region is critical for the development of cloned animals. However, in pigs, the imprinting and regulation of the DLK1-DIO3 region has not been systematically analyzed. The objective of this study was to investigate the imprinting status and methylatio...

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Bibliographic Details
Main Authors: Junliang Li, Dawei Yu, Jing Wang, Chongyang Li, Qingwei Wang, Weihua Du, Shanjiang Zhao, Yunwei Pang, Haisheng Hao, Xueming Zhao, Huabin Zhu, Shijie Li, Huiying Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pig
IG-DMR
DNA methylation
genomic imprinting
SCNT
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.964045/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.964045/full

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