Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.

The utrophin-dystrophin deficient (DKO) mouse model has been widely used to understand the progression of Duchenne muscular dystrophy (DMD). However, it is unclear as to what extent muscle pathology affects metabolism. Therefore, the present study was focused on understanding energy expenditure in t...

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Bibliographic Details
Main Authors: Meghna Pant, Danesh H Sopariwala, Naresh C Bal, Jeovanna Lowe, Dawn A Delfín, Jill Rafael-Fortney, Muthu Periasamy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4393257?pdf=render