T cell receptor richness in peripheral blood increases after cetuximab therapy and correlates with therapeutic response

T cell receptor richness in peripheral blood increases after cetuximab therapy and correlates with therapeutic response

The role of T cell receptor (TCR) signaling for adaptive immune responses is essential. The ability to respond to a broad spectrum of tumor antigens requires an adaptive selection of various TCR. So far, little is known about the role of TCR richness and clonality in the cellular immune response to...

Full description

Bibliographic Details
Main Authors: Benjamin A. Kansy, Gulidanna Shayan, Hyun-Bae Jie, Sandra P. Gibson, Yu L. Lei, Sven Brandau, Stephan Lang, Nicole C Schmitt, Fei Ding, Yan Lin, Robert L. Ferris
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:OncoImmunology
Subjects:
tcr
immunosequencing
cetuximab
egfr
cytotoxic t cells
head and neck cancer
immunotherapy
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1494112

Internet

http://dx.doi.org/10.1080/2162402X.2018.1494112

Similar Items