Haplotype analysis of BRCA1 intragenic markers in Iranian patients with familial breast and ovarian cancer
Background: Breast cancer is the most common malignancy in women. Breast Cancer Type 1 Susceptibility gene (BRCA1) is a tumor suppressor gene, involved in DNA damage repair and in 81% of the breast-ovarian cancer families were due to BRCA1. In some clinically investigated genes, the intragenic marke...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Shahid Sadoughi University of Medical Science, Yazd, Iran
2016-04-01
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Series: | Iranian Journal of Reproductive Medicine |
Online Access: | http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1907/970 |