The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy

Picornaviruses can escape infected cells via packaging in extracellular vesicles (EVs). Here, van der Grein et al. show that the non-structural Leader protein of encephalomyocarditis virus (EMCV) promotes the release of EV-enclosed virus particles and provide evidence for a role of secretory autopha...

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Bibliographic Details
Main Authors: Susanne G. van der Grein, Kyra A. Y. Defourny, Huib H. Rabouw, Soenita S. Goerdayal, Martijn J. C. van Herwijnen, Richard W. Wubbolts, Maarten Altelaar, Frank J. M. van Kuppeveld, Esther N. M. Nolte-‘t Hoen
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31181-y