Immune surveillance by rhinovirus-specific circulating CD4+ and CD8+ T lymphocytes.

It is difficult to experimentally infect volunteers with RV strains to which the subject demonstrates serological immunity. However, in RV challenges, viral clearance begins before de novo adaptive immune responses would develop. We speculated that adaptive immunity to RV reflects heterologous immun...

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Bibliographic Details
Main Authors: John W Steinke, Lixia Liu, Ronald B Turner, Thomas J Braciale, Larry Borish
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4293146?pdf=render