Molecular Characterization of Gastric Carcinoma: Therapeutic Implications for Biomarkers and Targets

Molecular Characterization of Gastric Carcinoma: Therapeutic Implications for Biomarkers and Targets

Palliative chemotherapy is the mainstay of treatment of advanced gastric carcinoma (GC). Monoclonal antibodies including trastuzumab, ramucirumab, and pembrolizumab have been shown to provide additional benefits. However, the clinical outcomes are often unpredictable and they can vary widely among p...

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Bibliographic Details
Main Authors: Lionel Kankeu Fonkoua, Nelson S. Yee
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Biomedicines
Subjects:
Asian Cancer Research Group (ACRG)
gastric carcinoma
molecular profiling
precision therapy
pembrolizumab
predictive biomarkers
ramucirumab
The Cancer Genome Atlas (TCGA)
therapeutic targets
trastuzumab
Online Access:http://www.mdpi.com/2227-9059/6/1/32

Internet

http://www.mdpi.com/2227-9059/6/1/32

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