Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer’s disease

Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer’s disease

Abstract Background Several evidences suggest that failure of synaptic function occurs at preclinical stages of Alzheimer’s disease (AD) preceding neuronal loss and the classical AD pathological hallmarks. Nowadays, there is an urgent need to identify reliable biomarkers that could be obtained with...

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Bibliographic Details
Main Authors: Dolores Siedlecki-Wullich, Judit Català-Solsona, Cristina Fábregas, Isabel Hernández, Jordi Clarimon, Alberto Lleó, Merce Boada, Carlos A. Saura, José Rodríguez-Álvarez, Alfredo J. Miñano-Molina
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Mild cognitive impairment
Synapses
miRNAs
Plasma
Human
Online Access:http://link.springer.com/article/10.1186/s13195-019-0501-4

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http://link.springer.com/article/10.1186/s13195-019-0501-4

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