Recombinant human erythropoietin accelerated the proliferation of non‐small cell lung cancer cell lines and reduced the expression of VEGF, HIF‐1α, and PD‐L1 under a simulated hypoxic environment in vitro

Recombinant human erythropoietin accelerated the proliferation of non‐small cell lung cancer cell lines and reduced the expression of VEGF, HIF‐1α, and PD‐L1 under a simulated hypoxic environment in vitro

Abstract Background As erythropoietin (EPO) has been used to treat anemia in cancer patients, negative controversy has continued. Unfortunately, its effects on non‐small‐cell lung carcinoma (NSCLC) cell lines are uncertain and the phenomenon of inducing immune escape of tumor cells remains to be exp...

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Bibliographic Details
Main Authors: Yajing Zhang, Yangchun Feng, Xiaojie Sun
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Chronic Diseases and Translational Medicine
Subjects:
cell proliferation
hypoxia
hypoxia‐inducible factor 1
non‐small cell lung cancer
vascular endothelial growth factor
Online Access:https://doi.org/10.1002/cdt3.12

Internet

https://doi.org/10.1002/cdt3.12

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