The <it>G-308A</it> variant of the Tumor Necrosis Factor-α (<it>TNF-α</it>) gene is not associated with obesity, insulin resistance and body fat distribution

<p>Abstract</p> <p>Background</p> <p>Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has been shown to induce insulin resistance, and a polymorphism at positio...

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Bibliographic Details
Main Authors: Vecci Elio, Berni Andrea, Arca Marcello, Capici Francesca, Sentinelli Federica, Romeo Stefano, Di Mario Umberto, Baroni Marco
Format: Article
Language:English
Published: BMC 2001-09-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/2/10