The <it>G-308A</it> variant of the Tumor Necrosis Factor-α (<it>TNF-α</it>) gene is not associated with obesity, insulin resistance and body fat distribution
<p>Abstract</p> <p>Background</p> <p>Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has been shown to induce insulin resistance, and a polymorphism at positio...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2001-09-01
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Series: | BMC Medical Genetics |
Online Access: | http://www.biomedcentral.com/1471-2350/2/10 |