The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy [version 1; peer review: 2 approved]

The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy [version 1; peer review: 2 approved]

Background: Animal models of Duchenne muscular dystrophy (DMD) are essential to study disease progression and assess efficacy of therapeutic intervention, however dystrophic mice fail to display a clinically relevant phenotype, limiting translational utility. Dystrophin-deficient dogs exhibit diseas...

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Bibliographic Details
Main Authors: Claire Massey, Emma M.A. Foster, Dominic J. Wells, Frances Taylor-Brown, Richard J. Piercy, Dominique O. Riddell, John C.W. Hildyard, Faye Rawson, Rachel C.M. Harron
Format: Article
Language:English
Published: Wellcome 2022-09-01
Series:Wellcome Open Research
Subjects:
DMD
Duchenne Muscular Dystrophy
Animal models
Dog
DE50-MD
Biomarkers
eng
Online Access:https://wellcomeopenresearch.org/articles/7-238/v1

Internet

https://wellcomeopenresearch.org/articles/7-238/v1

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