Optimal selection of specimens for metagenomic next-generation sequencing in diagnosing periprosthetic joint infections

Optimal selection of specimens for metagenomic next-generation sequencing in diagnosing periprosthetic joint infections

ObjectiveThis study aimed to assess the diagnostic value of metagenomic next-generation sequencing (mNGS) across synovial fluid, prosthetic sonicate fluid, and periprosthetic tissues among patients with periprosthetic joint infection (PJI), intending to optimize specimen selection for mNGS in these...

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Bibliographic Details
Main Authors: Jun Tan, Lingxiao Wu, Lijuan Zhan, Minkui Sheng, Zhongxin Tang, Jianzhong Xu, Haijun Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomic
prosthesis-related infections
next-generation sequencing - NGS
diagnosis
sonication
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1356804/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1356804/full

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