THE REASONS OF RESISTANCE TO THE TNF α INHIBITORS AND WAYS OF ITS OVERCOMING

The article presents a review of literature data, dedicated to problems of secondary ineffectiveness of infliximab in patients with rheumatoid arthritis. An analysis of available data showed that the main reason of resistance to the TNF α inhibitors is a synthesis of antibodies to the drug. Risk fac...

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Bibliographic Details
Main Authors: E.I. Alexeeva, A.A. Grigor'eva, R.V. Denisova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-11-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/1191