In Silico Profiling of Histone Deacetylase 8 Inhibitory Activity: A Computational Analysis of Novel Dipeptide-Based Compounds Cross-Linked with Hydroxamic Acid

This study involved the development of innovative compounds consisting of dipeptide cross-links combined with hydroxamic acid. Our objective was to assess their binding affinities with histone deacetylase 8 (HDAC8) by conducting a docking study, comparing the results with the reference ligand, sube...

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Bibliographic Details
Main Authors: omer mohammed ammash, Shakir M. Alwan, Ali R.M. albakaa, İsmail Alshrif Ibrheam ben Sulaiman
Format: Article
Language:English
Published: College of Pharmacy / Mustansiriyah University 2024-04-01
Series:Al-Mustansiriyah Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/1059