Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections

Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections

Thick, viscous respiratory secretions are a major pathogenic feature of COVID-19, but the composition and physical properties of these secretions are poorly understood. We characterized the composition and rheological properties (i.e., resistance to flow) of respiratory secretions collected from int...

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Bibliographic Details
Main Authors: Michael J. Kratochvil, Gernot Kaber, Sally Demirdjian, Pamela C. Cai, Elizabeth B. Burgener, Nadine Nagy, Graham L. Barlow, Medeea Popescu, Mark R. Nicolls, Michael G. Ozawa, Donald P. Regula, Ana E. Pacheco-Navarro, Samuel Yang, Vinicio A. de Jesus Perez, Harry Karmouty-Quintana, Andrew M. Peters, Bihong Zhao, Maximilian L. Buja, Pamela Y. Johnson, Robert B. Vernon, Thomas N. Wight, Stanford COVID-19 Biobank Study Group, Carlos E. Milla, Angela J. Rogers, Andrew J. Spakowitz, Sarah C. Heilshorn, Paul L. Bollyky
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-06-01
Series:JCI Insight
Subjects:
COVID-19
Pulmonology
Online Access:https://doi.org/10.1172/jci.insight.152629

Internet

https://doi.org/10.1172/jci.insight.152629

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