iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis

iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis

Abstract Introduction A pivotal effect of lymphatic vessel (LV) function in joint homeostasis was identified in the tumor necrosis factor-transgenic (TNF-Tg) mouse model of rheumatoid arthritis (RA). Specifically, loss of LV contractions is associated with progressive synovitis and erosions. Further...

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Bibliographic Details
Main Authors: Richard D. Bell, Pamelia N. Slattery, Emily K. Wu, Lianping Xing, Christopher T. Ritchlin, Edward M. Schwarz
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Arthritis Research & Therapy
Subjects:
Inducible nitric oxide synthase (iNOS)
Inflammatory arthritis
Lymph node
TNF
Online Access:http://link.springer.com/article/10.1186/s13075-019-2039-z

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http://link.springer.com/article/10.1186/s13075-019-2039-z

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