Lipid and Polymer-Based Nanoparticle siRNA Delivery Systems for Cancer Therapy

RNA interference (RNAi) uses small interfering RNAs (siRNAs) to mediate gene-silencing in cells and represents an emerging strategy for cancer therapy. Successful RNAi-mediated gene silencing requires overcoming multiple physiological barriers to achieve efficient delivery of siRNAs into cells in vi...

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Bibliographic Details
Main Authors: Francesco Mainini, Michael R. Eccles
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/11/2692