To Become or Not to Become Tumorigenic: Subventricular Zone Versus Hippocampal Neural Stem Cells

To Become or Not to Become Tumorigenic: Subventricular Zone Versus Hippocampal Neural Stem Cells

Neural stem cells (NSCs) persist in the adult mammalian brain in two neurogenic regions: the subventricular zone lining the lateral ventricles and the dentate gyrus of the hippocampus. Compelling evidence suggests that NSCs of the subventricular zone could be the cell type of origin of glioblastoma,...

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Bibliographic Details
Main Authors: Ángela Fontán-Lozano, Sara Morcuende, Mª América Davis-López de Carrizosa, Beatriz Benítez-Temiño, Rebeca Mejías, Esperanza R. Matarredona
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
neurogenesis
glioblastoma
neural stem cells
oncogenicity
cancer-driver mutations
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.602217/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.602217/full

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