The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of <i>erg</i>-mediated K<sup>+</sup> Currents

Isoplumbagin (isoPLB, 5-hydroxy-3-methyl-1,4-naphthoquinone), a naturally occurring quinone, has been observed to exercise anti-inflammatory, antimicrobial, and antineoplastic activities. Notably, whether and how isoPLB, plumbagin (PLB), or other related compounds impact transmembrane ionic currents...

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Bibliographic Details
Main Authors: Linyi Chen, Hsin-Yen Cho, Tzu-Hsien Chuang, Ting-Ling Ke, Sheng-Nan Wu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/4/780