Age-dependent inflammatory response is altered in an ex vivo model of bacterial pneumonia

Abstract Background Aging is associated with an increased incidence and mortality of Pseudomonas aeruginosa-induced pneumonias. This might be partly due to age-dependent increases in inflammatory mediators, referred to as inflamm-aging and a decline in immune functions, known as immunosenescence. St...

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Bibliographic Details
Main Authors: Charline Sommer, Stella Marie Reamon-Buettner, Monika Niehof, Christina Beatrix Hildebrand, Armin Braun, Katherina Sewald, Susann Dehmel, Christina Brandenberger
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02609-w