Single-cell transcriptome sequencing provides insight into multiple chemotherapy resistance in a patient with refractory DLBCL: a case report

Single-cell transcriptome sequencing provides insight into multiple chemotherapy resistance in a patient with refractory DLBCL: a case report

Relapsed and refractory diffuse large B-cell lymphoma (DLBCL) is associated with poor prognosis. As such, a comprehensive analysis of intratumoral components, intratumoral heterogeneity, and the immune microenvironment is essential to elucidate the mechanisms driving the progression of DLBCL and to...

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Bibliographic Details
Main Authors: Kewei Zhao, Qiuhui Li, Pengye Li, Tao Liu, Xinxiu Liu, Fang Zhu, Liling Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
diffuse large B-cell lymphoma
single-cell RNA sequencing
treatment resistance
tumor heterogeneity
tumor immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1303310/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1303310/full

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