Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes

Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes

Liver cirrhosis (LC), contributing to more than 1 million of deaths annually, is a major healthcare concern worldwide. Hepatitis B virus (HBV) is a major LC etiological factor, and 15% of patients with chronic HBV infection (CHB) develop LC within 5 years. Recently, novel host genetic determinants w...

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Bibliographic Details
Main Authors: Magda Rybicka, Anna Woziwodzka, Alicja Sznarkowska, Tomasz Romanowski, Piotr Stalke, Marcin Dręczewski, Eloi R. Verrier, Thomas F. Baumert, Krzysztof Piotr Bielawski
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
HBV
liver cirrhosis
genetic polymorphism
DNA repair
<i>XRCC1</i>
<i>ERCC2</i>
Online Access:https://www.mdpi.com/2072-6694/12/11/3295

Internet

https://www.mdpi.com/2072-6694/12/11/3295

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