The Modular Architecture of Metallothioneins Facilitates Domain Rearrangements and Contributes to Their Evolvability in Metal-Accumulating Mollusks

The Modular Architecture of Metallothioneins Facilitates Domain Rearrangements and Contributes to Their Evolvability in Metal-Accumulating Mollusks

Protein domains are independent structural and functional modules that can rearrange to create new proteins. While the evolution of multidomain proteins through the shuffling of different preexisting domains has been well documented, the evolution of domain repeat proteins and the origin of new doma...

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Bibliographic Details
Main Authors: Sara Calatayud, Mario Garcia-Risco, Veronika Pedrini-Martha, Michael Niederwanger, Reinhard Dallinger, Òscar Palacios, Mercè Capdevila, Ricard Albalat
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
protein modularity
domain repeat proteins
de novo domains
sORFs and lncRNAs
Cephalopoda and Caudofoveata MTs
Online Access:https://www.mdpi.com/1422-0067/23/24/15824

Internet

https://www.mdpi.com/1422-0067/23/24/15824

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