Cross protective immune responses in nursing piglets infected with a US spike-insertion deletion porcine epidemic diarrhea virus strain and challenged with an original US PEDV strain

Abstract We investigated cross-protective immunity of a US spike-insertion deletion porcine epidemic diarrhea virus (PEDV) Iowa106 (S-INDEL) strain against the original US PEDV (PC21A) strain in nursing piglets. Piglets were inoculated orally with S-INDEL, PC21A or mock. At 20–29 days post-inoculati...

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Bibliographic Details
Main Authors: Thavamathi Annamalai, Chun-Ming Lin, Xiang Gao, Xinsheng Liu, Zhongyan Lu, Linda J. Saif, Qiuhong Wang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-017-0469-7