Protective effects of a Modified Vaccinia Ankara-based vaccine candidate against Crimean-Congo Haemorrhagic Fever virus require both cellular and humoral responses.

Protective effects of a Modified Vaccinia Ankara-based vaccine candidate against Crimean-Congo Haemorrhagic Fever virus require both cellular and humoral responses.

Crimean-Congo Haemorrhagic Fever (CCHF) is a severe tick-borne disease, endemic in many countries in Africa, the Middle East, Eastern Europe and Asia. There is no approved vaccine currently available against CCHF. The most promising candidate, which has previously been shown to confer protection in...

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Bibliographic Details
Main Authors: Stuart D Dowall, Victoria A Graham, Emma Rayner, Laura Hunter, Robert Watson, Irene Taylor, Antony Rule, Miles W Carroll, Roger Hewson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4896484?pdf=render

Internet

http://europepmc.org/articles/PMC4896484?pdf=render

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