OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression

OxLDL sensitizes platelets for increased formation of extracellular vesicles capable of finetuning macrophage gene expression

Platelet extracellular vesicles (PEVs) generated upon platelet activation may play a role in inflammatory pathologies such as atherosclerosis. Oxidized low-density lipoprotein (oxLDL), a well-known contributor to atherogenesis, activates platelets and presensitizes them for activation by other agoni...

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Bibliographic Details
Main Authors: Katariina Maaninka, Maarit Neuvonen, Erja Kerkelä, Kati Hyvärinen, Mari Palviainen, Masood Kamali-Moghaddam, Antonio Federico, Dario Greco, Saara Laitinen, Katariina Öörni, Pia RM Siljander
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
Extracellular vesicle
Platelet
Oxidized low-density lipoprotein
Atherosclerosis
Macrophage
Transcriptome
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000262

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http://www.sciencedirect.com/science/article/pii/S0171933523000262

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