Defining matrix Gla protein expression in the Dunkin-Hartley guinea pig model of spontaneous osteoarthritis

Defining matrix Gla protein expression in the Dunkin-Hartley guinea pig model of spontaneous osteoarthritis

Abstract Background Matrix Gla (γ-carboxyglutamate) protein (MGP) is considered a strong inhibitor of ectopic calcification, and it has been associated with OA severity, although not conclusively. We utilized male Dunkin-Hartley (DH) guinea pigs to investigate the expression of MGP throughout aging...

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Bibliographic Details
Main Authors: Xun Ma, Zhan Zhang, Xinyuan Kang, Chunbo Deng, Yingwei Sun, Yanjun Li, Desheng Huang, Xueyong Liu
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Musculoskeletal Disorders
Subjects:
Matrix Gla protein
Osteoarthritis
Guinea pig
Proteomics
Online Access:https://doi.org/10.1186/s12891-021-04735-2

Internet

https://doi.org/10.1186/s12891-021-04735-2

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