Development of a cancer metastasis-on-chip assay for high throughput drug screening

Metastasis is the cause of most triple-negative breast cancer deaths, yet anti-metastatic therapeutics remain limited. To develop new therapeutics to prevent metastasis, pathophysiologically relevant assays that recapitulate tumor microenvironment is essential for disease modeling and drug discovery...

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Bibliographic Details
Main Authors: Lutfiye Yildiz Ozer, Hend Salah Fayed, Johan Ericsson, Ayman Al Haj Zen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1269376/full