The Ratio of von Willebrand Factor Antigen to ADAMTS13 Activity: Usefulness as a Prognostic Biomarker in Acute-on-Chronic Liver Failure

The Ratio of von Willebrand Factor Antigen to ADAMTS13 Activity: Usefulness as a Prognostic Biomarker in Acute-on-Chronic Liver Failure

Acute-on-chronic liver failure (ACLF) has a high risk of short-term mortality. A disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) is a metalloproteinase that specifically cleaves multimeric von Willebrand factor (VWF). Imbalance between ADAMTS13 and VWF is assoc...

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Bibliographic Details
Main Authors: Hiroaki Takaya, Tadashi Namisaki, Masahide Enomoto, Takahiro Kubo, Yuki Tsuji, Yukihisa Fujinaga, Norihisa Nishimura, Kosuke Kaji, Hideto Kawaratani, Kei Moriya, Takemi Akahane, Masanori Matsumoto, Hitoshi Yoshiji
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biology
Subjects:
ADAMTS13
von Willebrand factor
biomarkers
liver cirrhosis
acute-on-chronic liver failure
Online Access:https://www.mdpi.com/2079-7737/12/2/164

Internet

https://www.mdpi.com/2079-7737/12/2/164

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