Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose

Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose

Abstract Background The Plasmodium falciparum sexual-stage surface proteins Pfs25 and Pfs230 are antigen candidates for a malaria transmission-blocking vaccine (TBV), and have been widely investigated as such. It is not clear whether simultaneously presenting these two antigens in a particulate vacc...

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Bibliographic Details
Main Authors: Wei-Chiao Huang, Bingbing Deng, Moustafa T. Mabrouk, Amal Seffouh, Joaquin Ortega, Carole Long, Kazutoyo Miura, Yimin Wu, Jonathan F. Lovell
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Malaria Journal
Subjects:
Pfs25
Pfs230
Malaria
Transmission-blocking vaccine
Liposomes
Online Access:http://link.springer.com/article/10.1186/s12936-020-03368-5

Internet

http://link.springer.com/article/10.1186/s12936-020-03368-5

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