Metabolism-based approaches for autosomal dominant polycystic kidney disease

Metabolism-based approaches for autosomal dominant polycystic kidney disease

Autosomal Dominant Polycystic Kidney Disease (ADPKD) leads to end stage kidney disease (ESKD) through the development and expansion of multiple cysts throughout the kidney parenchyma. An increase in cyclic adenosine monophosphate (cAMP) plays an important role in generating and maintaining fluid-fil...

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Bibliographic Details
Main Authors: Ivona Bakaj, Alessandro Pocai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
ADPKD (autosomal dominant polycystic kidney disease)
tolvaptan
metabolic reprograming
therapeutic approaches
metabolism & obesity
GLP-1
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1126055/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1126055/full

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