The immunomodulatory activity of meningococcal lipoprotein Ag473 depends on the conformation made up of the lipid and protein moieties.

We have previously demonstrated that the meningococcal antigen Ag473 in the presence of Freund's adjuvant can elicit protective immune responses in mouse challenge model. In this study, we evaluated the structural requirement for the immunological activity and the possible signaling pathway of...

Full description

Bibliographic Details
Main Authors: Ching-Liang Chu, Yen-Ling Yu, Yueh-Chen Kung, Pei-Yu Liao, Ko-Jiunn Liu, Yen-Tzu Tseng, Yuan-Chuen Lin, Steve Shih-Yang Hsieh, Pele Choi-Sing Chong, Chiou-Ying Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22844415/?tool=EBI