Two modes of transcriptional activation at native promoters by NF-kappaB p65.

The NF-kappaB family of transcription factors is crucial for the expression of multiple genes involved in cell survival, proliferation, differentiation, and inflammation. The molecular basis by which NF-kappaB activates endogenous promoters is largely unknown, but it seems likely that it should incl...

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Bibliographic Details
Main Authors: Dominic van Essen, Bettina Engist, Gioacchino Natoli, Simona Saccani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2661965?pdf=render