Two modes of transcriptional activation at native promoters by NF-kappaB p65.
The NF-kappaB family of transcription factors is crucial for the expression of multiple genes involved in cell survival, proliferation, differentiation, and inflammation. The molecular basis by which NF-kappaB activates endogenous promoters is largely unknown, but it seems likely that it should incl...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC2661965?pdf=render |