Impact of p85α Alterations in Cancer

The phosphatidylinositol 3-kinase (PI3K) pathway plays a central role in the regulation of cell signaling, proliferation, survival, migration and vesicle trafficking in normal cells and is frequently deregulated in many cancers. The p85α protein is the most characterized regulatory subunit of the cl...

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Bibliographic Details
Main Authors: Jeremy D. S. Marshall, Dielle E. Whitecross, Paul Mellor, Deborah H. Anderson
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/9/1/29