Kinetics of myelin breakdown products: A labeling study in patients with progressive multiple sclerosis

Abstract The majority of disease modifying therapies for multiple sclerosis (MS) reduce inflammation, but do no’t target remyelination. Development of remyelinating therapies will benefit from a method to quantify myelin kinetics in patients with MS. We labeled myelin in vivo with deuterium, and mod...

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Bibliographic Details
Main Authors: Kawita M. S. Kanhai, Sebastiaan C. Goulooze, Jeroen van derGrond, Amy C. Harms, Thomas Hankemeier, Ajay Verma, Gersham Dent, Juan Chavez, Henri Meijering, Geert Jan Groeneveld
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13181