Association between CYP2C9 and CYP2C19 Polymorphism, Metabolism, and Neurotoxicity after Administration of Phenytoin: A Systematic Review
Abstract—Phenytoin is an antiepileptic drug (AED) metabolized by cytochrome P450 enzymes, especially by CYP2C9 (90%) and CYP2C19 (10%), where both enzymes are polymorphic so that they can undergo polymorphism and it can change the metabolic rate of the drug. Phenytoin is one of the drugs whose risk...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Direktorat Penerbitan dan Publikasi Ilmiah Universitas Surabaya
2023-12-01
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| Series: | Keluwih |
| Subjects: | |
| Online Access: | https://journal.ubaya.ac.id/index.php/kesdok/article/view/6010 |