NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma

Abstract Background Melanoma is a highly heterogeneous cancer, in which frequent changes in activation of signaling pathways lead to a high adaptability to ever changing tumor microenvironments. The elucidation of cancer specific signaling pathways is of great importance, as demonstrated by the inhi...

Full description

Bibliographic Details
Main Authors: Lucia Devitt, Dana Westphal, Katharina Pieger, Nadja Schneider, Anja Katrin Bosserhoff, Silke Kuphal
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01632-8