Obesity accelerates age defects in B cells, and weight loss improves B cell function

Obesity accelerates age defects in B cells, and weight loss improves B cell function

Abstract Background We have previously shown that obesity accelerates age-associated defects in B cell function and antibody production leading to decreased secretion of protective antibodies and increased autoimmunity. We wanted to evaluate if obese adults enrolled in a voluntary weight reduction p...

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Bibliographic Details
Main Authors: Daniela Frasca, Maria Romero, Alain Diaz, Bonnie B. Blomberg
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Immunity & Ageing
Subjects:
Aging
Obesity
B cells
Humoral immunity
Influenza vaccination
Online Access:https://doi.org/10.1186/s12979-023-00361-9

Internet

https://doi.org/10.1186/s12979-023-00361-9

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