Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation

Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation

Abstract Background Migraine stands as a prevalent primary headache disorder, with prior research highlighting the significant involvement of oxidative stress and inflammatory pathways in its pathogenesis and chronicity. Existing evidence indicates the capacity of Dl-3-n-butylphthalide (NBP) to miti...

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Bibliographic Details
Main Authors: Yingyuan Liu, Zihua Gong, Deqi Zhai, Chunxiao Yang, Guangshuang Lu, Shuqing Wang, Shaobo Xiao, Chenhao Li, Ludan Chen, Xiaoxue Lin, Shuhua Zhang, Shengyuan Yu, Zhao Dong
Format: Article
Language:English
Published: BMC 2024-04-01
Series:The Journal of Headache and Pain
Subjects:
NBP
Nrf2
Neuroinflammation
Oxidative stress
Central sensitization
Migraine
Online Access:https://doi.org/10.1186/s10194-024-01750-1

Internet

https://doi.org/10.1186/s10194-024-01750-1

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