C646 Protects Against DSS-Induced Colitis Model by Targeting NLRP3 Inflammasome

C646 Protects Against DSS-Induced Colitis Model by Targeting NLRP3 Inflammasome

Numerous pieces of evidence have identified that the NLRP3 inflammasome plays a pivotal role in the development and pathogenesis of colitis. Targeting the NLRP3 inflammasome represents a potential therapeutic treatment. Our previous studies have suggested that acetylation of NLRP3 is indispensable t...

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Bibliographic Details
Main Authors: Xueming Xu, Jing Li, Xiuyan Long, Sifan Tao, Xiaoyu Yu, Xixian Ruan, Kai Zhao, Li Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
C646
DSS-induced
NLRP3 inflammsome
NF-κB
ASC speck
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.707610/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.707610/full

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