Inhibition of the Cell Uptake of Delta and Omicron SARS-CoV-2 Pseudoviruses by <i>N</i>-Acetylcysteine Irrespective of the Oxidoreductive Environment

The binding of SARS-CoV-2 spikes to the cell receptor angiotensin-converting enzyme 2 (ACE2) is a crucial target both in the prevention and in the therapy of COVID-19. We explored the involvement of oxidoreductive mechanisms by investigating the effects of oxidants and antioxidants on virus uptake b...

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Bibliographic Details
Main Authors: Sebastiano La Maestra, Silvano Garibaldi, Roumen Balansky, Francesco D’Agostini, Rosanna T. Micale, Silvio De Flora
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/20/3313